榪戞棩錛?/span>鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈湪緹庡鎶よ偆琛屼笟涓紩鍙戜簡騫挎硾鍏蟲敞鍜岀儹璁紝鎴愪負(fù)浜嗕紬澶氱埍緹庝漢澹拷鎹х殑鐒︾偣銆傝繖涓�鍒涙柊鎬х殑鎶�鏈負(fù)鍥版壈浜轟滑宸蹭箙鐨勮壊鏂戦棶棰樺甫鏉ヤ簡鍏ㄦ柊鐨勮В鍐蟲柟妗堬紝鏈夋湜閲嶅緹庣櫧紲涙枒棰嗗煙鐨勬牸灞�銆?/span>
鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈殑鍘熺悊鏄熀浜?/span> 2006 騫磋璐濆皵鐢熺悊瀛﹀尰瀛﹀鐨?鈥?/span>鏍擱吀錛?/span>RNA錛夊共鎵版満鍒?/span>鈥?/span>銆傝鎶�鏈兘澶熺洿鎺ヤ綔鐢ㄤ簬鐨偆鐨勫熀搴曞眰錛岄�氳繃鎺у埗榛戣壊绱犲熀鍥犵殑琛ㄨ揪錛岄樆姝㈤粦鑹茬礌鐨勫垎娉屽拰鐢熸垚錛屼粠鏍規(guī)簮涓婅В鍐寵壊鏂戦棶棰?銆備笌浼犵粺鐨勭編鐧界鏂戞柟娉曠浉姣旓紝鏍哥硸鏍擱吀鎶�鏈叿鏈夋洿楂樼殑綺懼噯鎬у拰鏈夋晥鎬э紝鑳藉瀹炵幇鏇村交搴曠殑紲涙枒鏁堟灉錛屽茍涓斾笉鏄撳弽寮廣�?/span>
浼楀鐭ュ悕緹庡鎶よ偆鍝佺墝綰風(fēng)悍鎶曞叆鍒?/span>鏍哥硸鏍擱吀緹庣櫧紲涙枒浜у搧鐨勭爺鍙戝拰鎺ㄥ箍涓�備緥濡傦紝緹庢⒌寰?/span>鐨?/span>鏍哥硸鏍擱吀紲涙枒榛勯噾緇勫悎涓�緇忔帹鍑猴紝渚垮彈鍒頒簡甯傚満鐨勯珮搴﹁鍙�傝浜у搧涓嶄粎鑾峰緱浜嗗浗瀹墮鍝佽嵂鍝佺洃鐫ｇ鐞嗘�誨眬鐨勭壒孌婄敤閫斿寲濡嗗搧緹庣櫧紲涙枒鍥藉鐗硅瘉錛岃繕鍑�熷叾鍗撹秺鐨勬晥鏋滃拰瀹夊叏鎬э紝璧㈠緱浜嗘秷璐硅�呯殑淇¤禆銆傛嵁浣跨敤鑰呭弽棣堬紝浣跨敤緹庢⒌寰?/span>鐨?/span>鏍哥硸鏍擱吀紲涙枒浜у搧鍚庯紝鑹叉枒鏄庢樉娣″寲錛岃倢鑲ゅ彉寰楁洿鍔犵櫧鐨欍�佸厜婊戯紝鐒曞彂鍑哄仴搴風(fēng)殑鍏夊僵銆?/span>
闄や簡緹庢⒌寰?/span>錛屽叾浠栧搧鐗岀殑鏍哥硸鏍擱吀緹庣櫧紲涙枒浜у搧涔熷湪甯傚満涓婇�愭笎宕湶澶磋銆傝繖浜涗駭鍝佸湪鎴愬垎鍜屾妧鏈笂涓嶆柇鍒涙柊錛屽姏姹備負(fù)娑堣垂鑰呮彁渚涙洿浼樿川鐨勭編鐧界鏂戜綋楠屻�備緥濡傦紝鏈夌殑浜у搧娣誨姞浜嗗縐嶇弽璐電殑妞嶇墿鎻愬彇鐗╁拰媧繪�ф垚鍒嗭紝涓?/span>鏍哥硸鏍擱吀鎶�鏈浉緇撳悎錛岃兘澶熻繘涓�姝ュ寮虹鏂戞晥鏋滐紝鍚屾椂婊嬪吇鑲岃偆錛屾彁楂樿倢鑲ょ殑鎶墊姉鍔涖�?/span>
琛屼笟涓撳瀵?/span>鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈殑鍙戝睍鍓嶆櫙鍏呮弧淇″績銆備粬浠涓猴紝闅忕潃浜轟滑瀵圭編瀹規(guī)姢鑲ら渶姹傜殑涓嶆柇鎻愰珮錛屼互鍙?qiáng)瀵箍U戝鎶�鏈殑淇′換搴﹀鍔狅紝鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈皢鎴愪負(fù)鏈潵緹庡鎶よ偆琛屼笟鐨勪富嫻佽秼鍔褲�傚悓鏃訛紝涓撳涔熸彁閱掓秷璐硅�咃紝鍦ㄩ�夋嫨鏍哥硸鏍擱吀緹庣櫧紲涙枒浜у搧鏃訛紝瑕佹敞鎰忛�夋嫨姝ｈ鍝佺墝鍜屾湁璧勮川鐨勪駭鍝侊紝閬垮厤璐拱鍒板亣鍐掍吉鍔ｄ駭鍝併�?/span>
鍦ㄥ競鍦洪渶姹傜殑鎺ㄥ姩涓嬶紝鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈殑鐮斿彂鍜屽簲鐢ㄥ皢涓嶆柇娣卞叆銆傛湭鏉ワ紝鎴戜滑鏈夋湜鐪嬪埌鏇村鍒涙柊鐨?/span>鏍哥硸鏍擱吀緹庣櫧紲涙枒浜у搧闂笘錛屼負(fù)娑堣垂鑰呭甫鏉ユ洿澶氱殑鎯婂枩鍜岄�夋嫨銆傜浉淇″湪鏍哥硸鏍擱吀緹庣櫧紲涙枒鎶�鏈殑寮曢涓嬶紝緹庡鎶よ偆琛屼笟灝嗚繋鏉ユ洿鍔犵編濂界殑鍙戝睍鍓嶆櫙銆?/span>